autophag相关论文
Mammalian target of rapamycin (mTOR) is a conserved Ser/Thr kinase that includes mTOR complex (mTORC) 1 and mTORC2.The m......
Calpains are a group of calcium-dependent proteases that are over activated by increased intracellular calcium levels un......
,Establishing a novel C.elegans model to investigate the role of autophagy in amyotrophic lateral sc
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【目的】探讨丹参静脉滴注对早期糖尿病肾病(Diabetic nephropathy,DN)患者外周血自噬相关蛋白表达的影响。【方法】61例早期DN患......
目的 研究新生期大鼠反复惊厥后海马中自噬标记蛋白微管相关蛋白1轻链3(LC3)的表达及3-MA对表达的干预作用.方法 实验在苏州大学衰......
[HTH]目的[HTSS]研究远隔缺血预适应(remote ischemic preconditioning,RIPC)对局灶性脑缺血再灌注大鼠缺血半暗带区自噬相关蛋白B......
Reduced radiosensitivity of lung cancer cells represents a pivotal obstacle in clinical oncology. The hypoxia-inducible ......
目的探讨Alisertib(ALS)对人结直肠癌Caco-2和HT29细胞的诱导自噬的作用及与p53表达状态间的关系。方法本研究采用人结直肠癌Caco-......
目的 研究树脂单体甲基丙烯酸羟乙酯(2-Hydroxyethyl methacrylate,HEMA)对人牙源性间充质细胞(dental mesenchymal cells,DMCs)的......
目的研究Apelin-13对于小鼠脑出血(ICH)后自噬相关蛋白(autophagy)的影响,并初步探讨其调节机制。方法正常CD-1小鼠纹状体注射胶原酶Ⅳ......
目的探讨沉默烯酰辅酶A水合酶短链1(ECHS1)表达对结肠癌HT-29细胞自噬的影响及可能作用机制。方法将ECHS1 shRNA质粒及阴性质粒转......
目的探讨自噬相关蛋白SQSTM1/p62(p62)和雷帕霉素靶蛋白(mTOR)在非小细胞肺癌(NSCLC)中的表达及临床意义。方法选择80例确诊为NSCL......
目的建立靶向人Beclinl非编码区小分子干扰(siRNA)的方法并对其效果进行评价。方法设计分别靶向人BeclinlmRNA不同区域的siRNA:靶向5......
目的:探讨白藜芦醇通过调控微小RNA-34a(miR-34a)表达对骨肉瘤MG-63细胞生长、侵袭和自噬的影响。方法:将骨肉瘤MG-63细胞分为对照组及......
Resveratrol Induces Apoptosis and Autophagy in T-cell Acute Lymphoblastic Leukemia Cells by Inhibiti
Objective To explore the effects of resveratrol-induced apoptosis and autophagy in T-cell acute lymphoblastic leukemia(T......
多发性硬化(MS)是全球分布的中枢神经系统(CNS)自身免疫性脱髓鞘疾病,目前认为其发病是基因易感性与环境因素双重作用的结果。瓜氨......
目的研究YB-1抑制三氧化二砷(As2O3)诱导人胃癌BGC-823细胞自噬的机制。方法采用脂质体转染siRNA干扰YB-1和腺病毒转染pAdlEasy/YB-1......
目的观察治疗性低温(TH)在缺氧期对心肌细胞自噬活性及自噬流的影响,并探讨其作用机制。方法取大鼠心肌细胞株H9c2,分为对照组、缺氧......
目的:观察20(S)-原人参二醇(PPD)对人子宫颈癌siha细胞生长的抑制作用及其对自噬基因Beclin1及MAP1-LC3转录和表达的影响,探讨PPD抑制si......
Cardiovascular diseases are the number one cause of morbidity and mortality in the United States and worldwide.The induc......
Mu-Xiang-You-Fang protects PC12 cells against OGD/R-induced autophagy via AMPK/mTOR signaling pathwa
OBJECTIVE Mu-Xiang-You-Fang(MXYF)is a classic prescription of Hui medicine,composed of five herbs,which has been used to......
Correlation of contrast-enhanced ultrasonography parameters of thyroid cancer with the expression of
Objective: To explore the correlation of contrast-enhanced ultrasonography parameters of thyroid cancer with the express......